Milestones

2013
# Milestone name Leader Date Comments WP
MS1 Results literature search and reviewing protocol IOM Dec-13 Document distributed to partners in WP1 WP1
MS34 Organizational setup of Workshop on interdisciplinary communication and the exposome concept LMU Dec-13 First event on M12. Then every 12 months (M24, M36, M48) WP18
2014
# Milestone name Leader Date Comments WP
MS4 Selection of cohort samples for omics pilots TNO Mar-14 In collaboration with all WPs from Stream 5 WP5
MS13 Technical evaluation of the cohort studies and their representativeness IOM Mar-14  – WP9
MS19 Completion of review of the literature and identification of gaps CNR Mar-14 Review Papers WP14
MS23 Completion of review of the literature and identification of gaps ISS Mar-14 Review papers WP15
MS27 Completion of review of the literature and identification of gaps UPMC Mar-14 Review papers WP16
MS37 HEALS website operational CSIC Mar-14  – WP19
MS2 Organizational setup of HBM back to back ?omics workshop JSI Jun-14 Actual date chosen for organisation of workshop in collaboration with WP5 and Stream 5 WP4
MS5 SOPs and protocols on biological matrices foreseen of relevance to HEALS TNO Aug-14 Delivery date: M11 and progressing in time WP5
MS7 Check on available data for lifespan PBPK model AUTH Sep-14 In collaboration with WP7, WP12 and Stream 5 WP6
MS8 Omics data availability for integrative bioinformatics approaches AUTH Sep-14 Delivery date: M12 (on public data)-and accumulating with HEALS specific data WP7
MS15 Completion of overview of available tools, methods and databases to be included in the HEALS platfor VTT Sep-14 In collaboration with all WPs in Streams 2,3,5. WP12
MS20 Completion of data harmonisation CNR Sep-14 Database and technical report WP14
MS24 Completion of data harmonisation ISS Sep-14 Database and technical report WP15
MS28 Completion of data harmonisation UPMC Sep-14 Database and technical report WP16
MS35 Organizational setup of training workshop LMU Sep-14  – WP18
MS38 Dissemination strategy Established CSIC Sep-14  – WP19
2015
# Milestone name Leader Date Comments WP
MS16 Design of the HEALS database platform VTT Jan-15  – WP12
MS11 Implementation of external exposome variables UOWM Mar-15  – WP8
MS9 Omics data analysis completed AUTH Jul-15 In collaboration with WP5 WP7
MS3 Bioinformatics tools applied to environmental and biomarker data JSI Sep-15 In collaboration with WP5 WP4
MS10 Completed selection of chemical stressors, in vitro models and systems biology modelling approaches AUTH Sep-15 Delivery date: M24, and in time iteratively in interaction between systems biology modelling and in vitro experimentation WP7
MS12 Preliminary concept of a computational model for the analysis of the impact of external exposome on UOWM Sep-15  – WP8
MS14 Agreement on methodologies for remote sensor-based individual exposure and health data UNIVBRIS Sep-15  – WP10
2016
# Milestone name Leader Date Comments WP
MS6 Selection of cohort samples jointly with selection of omics technologies for application in exposome TNO Mar-16 In collaboration with all WPs from Stream 3 and Stream 5 WP5
MS21 Completion of external exposure assessment CNR Mar-16 Delivery date: M30 up to M40 WP14
MS25 Completion of external exposure assessment ISS Mar-16 Delivery date: M30 up to M40 WP15
MS29 Completion of external exposure assessment UPMC Mar-16 Delivery date: M30 up to M40 WP16
MS31 Completion of external exposure assessment UPMC Mar-16 Delivery date: M30 up to M40 WP17
MS36 Materials on use of biomarkers and ?omics technologies for external training LMU Mar-16  – WP18
2017
# Milestone name Leader Date Comments WP
MS17 Completion of integration of dataset and models into the HEALS platform UPMC Jan-17 In collaboration with all WPs in Stream 2,3,5. WP13
MS22 Completion of internal exposure assessment CNR Jan-17 Methodological report WP14
MS26 Completion of external exposure assessment ISS Jan-17 Methodological report WP15
MS30 Completion of internal exposure assessment UPMC Jan-17 Methodological report WP16
MS32 Completion of internal exposure assessment UPMC Jan-17 Methodological report WP17
MS18 Completion of HEALS Approach UPMC Mar-17 In collaboration with all WPs in Stream 2,3,5. WP13
2018
# Milestone name Leader Date Comments WP
MS33 Completion of EXHES (Twin and singleton Follow-up Study) on use of biomarkers and ?omics technologie UPMC Mar-18  – WP17
MS39 HEALS Publications CSIC Sep-18  – WP19